Dose-effect relationship between premature chromosome and irradiation dose / 中华劳动卫生职业病杂志
Chinese Journal of Industrial Hygiene and Occupational Diseases
;
(12): 714-717, 2007.
Artículo
en Chino
| WPRIM
| ID: wpr-338934
ABSTRACT
<p><b>OBJECTIVE</b>To explore the dose-effect relationship between premature chromosome condensation induced by Calyculin A and irradiation dose.</p><p><b>METHODS</b>The human peripheral blood was irradiated by (137)Cs gamma radial. The irradiation dose included 0, 0.5, 1.0, 2.0, 3.0, 4.0, 5.0 Gy. The premature chromosome condensation induced by Calyculin A was observed, and dyed by centromeric banding.</p><p><b>RESULTS</b>There was the quadratic relation between the total aberration, fragment, dicentric+centric ring (dic+r) ration and irradiation dose.</p><p><b>CONCLUSION</b>Premature chromosome condensation induced by Calyculin A can be used as a biodosimetry.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Oxazoles
/
Farmacología
/
Efectos de la Radiación
/
Linfocitos
/
Línea Celular
/
Aberraciones Cromosómicas
/
Bandeo Cromosómico
/
Cromosomas
/
Relación Dosis-Respuesta en la Radiación
/
Rayos gamma
Límite:
Femenino
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
Chinese Journal of Industrial Hygiene and Occupational Diseases
Año:
2007
Tipo del documento:
Artículo
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