Magnetic resonance imaging diagnosis of grades I and II ganglioglioma / 南方医科大学学报

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the magnetic resonance imaging (MRI) findings and clinical features of grades I and II gangliogliomas and improve their diagnostic accuracy.</p><p><b>METHODS</b>Fourteen patients with grade I or II ganglioglioma underwent plain MRI and contrast-enhanced T1-weighted imaging (T1WI).</p><p><b>RESULTS</b>Eleven supratentorial and 3 infratentorial gangliogliomas were identified in these patients including 13 patients below 30 years and 11 with epilepsy. All the 14 patients showed hypointense tumors on T1WI and hyperintense lesions on T2WI, and 4 showed solitary cystic foci (including 2 patients with grade I and 2 with grade II gangliogliomas). Contrasted T1WI revealed no enhancement in 5 patients (4 with grade I and 1 with grade II gangliogliomas), diffuse mild enhancement in the foci in 3 patients with grade II gangliogliomas, gyrus-like enhancement in 4 patients (2 with grade I and 2 with grade II gangliogliomas), and intense enhancement in the nodules on the capsule wall in 2 grade II patients.</p><p><b>CONCLUSION</b>Grades I and II gangliogliomas may present with characteristic MRI findings, which may help improve the diagnostic accuracy of gangliogliomas in combination with patients' clinical data and onset age.</p>