Effect of fetus hypobaric hypoxia on NMDA receptor of hippocampus neurons / 中国应用生理学杂志
Chinese Journal of Applied Physiology
;
(6): 321-323, 2002.
Artículo
en Chino
| WPRIM
| ID: wpr-339728
ABSTRACT
<p><b>AIM</b>To study the effect of fetus hypobaric hypoxia on the number and channel character of NMDA receptor of hippocampus neurons.</p><p><b>METHODS</b>Use in situ hybridization and patch-clamp techniques.</p><p><b>RESULTS</b>After hypobaric hypoxia the number of NMDA mRNA positive neurons was decreased, the open probability of NMDA receptor was reduced, the open time constant was decreased, the close time constant was increased.</p><p><b>CONCLUSION</b>Hypobaric hypoxia may change the development of NMDA receptor in fetus rat, then maybe effect learning and memory.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Patología
/
ARN Mensajero
/
Hipoxia de la Célula
/
N-Metilaspartato
/
Hibridación in Situ
/
Receptores de N-Metil-D-Aspartato
/
Técnicas de Placa-Clamp
/
Hipotensión Intracraneal
/
Biología Celular
/
Feto
Límite:
Animales
Idioma:
Chino
Revista:
Chinese Journal of Applied Physiology
Año:
2002
Tipo del documento:
Artículo
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