Research progress in the structure and fuction of Orthopoxvirus host range genes / 病毒学报
Chinese Journal of Virology
;
(6): 437-441, 2013.
Artículo
en Chino
| WPRIM
| ID: wpr-339931
ABSTRACT
Orthopoxvirus vector has a broad prospect in recombinant vaccine research, but the rarely severe side-effect impedes its development. Vaccinia virus and Cowpox virus of Orthopoxvirus have broad host range, and they have typical host range genes as K1L, CP77 and C7L. These three genes affect host range of Vaccinia virus, disturb the cell signaling pathways, suppress immune response and are related to virulence.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fisiología
/
Virus Vaccinia
/
Proteínas Virales
/
Virulencia
/
Vacunas Virales
/
Vacunas Sintéticas
/
Transducción de Señal
/
Virus de la Viruela Vacuna
/
Línea Celular
/
Orthopoxvirus
Idioma:
Chino
Revista:
Chinese Journal of Virology
Año:
2013
Tipo del documento:
Artículo
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