Difference in lymphocyte heat shock protein 71 (HSP71) expression in soldiers of armed police forces from different climatic zones / 中华劳动卫生职业病杂志
Chinese Journal of Industrial Hygiene and Occupational Diseases
; (12): 282-284, 2002.
Article
en Zh
| WPRIM
| ID: wpr-340082
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To analyze the difference between basal and heat-inducible levels of lymphocyte heat shock protein 71 (HSP71) expression in soldiers from Beijing, Zhengzhou and Guangzhou.</p><p><b>METHODS</b>Flow cytometry and Comet assay were used to detect the level of HSP71 and DNA damage respectively.</p><p><b>RESULTS</b>Comet assay showed that there was no significant DNA damage before and after heat stress at 41 degrees C for 1 h, and also no difference found among the 3 climatic zones(P > 0.05). HSP71 of all soldiers in the 3 zones elevated after stress (P < 0.05). The basal and heat-inducible levels of HSP71 in Beijing soldiers(845.87 +/- 135.60 and 1254. 47 +/- 239.05 mean fluorescence intensity respectively) were higher than those in Guangzhou soldiers(702.73 +/- 184.70 and 861.72 +/- 225.12 mean fluorescence intensity respectively) (P < 0.05).</p><p><b>CONCLUSION</b>The differences of lymphocyte HSP71 expression before and after heat stress among the soldiers from Beijing, Zhengzhou and Guangzhou suggest that basal and heat-inducible levels of lymphocyte HSP71 expression may be considered as a valuable index to evaluate heat tolerance of soldiers in different climatic zones.</p>
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Índice:
WPRIM
Asunto principal:
Daño del ADN
/
Linfocitos
/
Policia
/
Clima
/
Trastornos de Estrés por Calor
/
Ensayo Cometa
/
Citometría de Flujo
/
Proteínas de Choque Térmico
/
Metabolismo
/
Personal Militar
Límite:
Humans
Idioma:
Zh
Revista:
Chinese Journal of Industrial Hygiene and Occupational Diseases
Año:
2002
Tipo del documento:
Article