Klebsiella pneumoniae: epidemiology and analysis of risk factors for infections caused by resistant strains / 中华医学杂志(英文版)
Chinese Medical Journal
;
(24): 1158-1162, 2002.
Artículo
en Inglés
| WPRIM
| ID: wpr-340367
ABSTRACT
<p><b>OBJECTIVE</b>To analyze the epidemiology of hospital and community-acquired infections caused by Klebsiella pneumoniae (K. pneumoniae) and risk factors for infections caused by resistant strains.</p><p><b>METHODS</b>A retrospective observational study was performed to analyze the relationship between antimicrobial use and bacterial resistance.</p><p><b>RESULTS</b>A K. pneumoniae infection was diagnosed in 0.47% of patients (169 of 36 179) admitted to the hospital between 1 March 1999 and 31 August 2000. Of the 169 isolates, 166 (98.2%) were resistant to at least one antimicrobial and 91.1% (154/169) to two or more antibiotics. 98% were resistant to ampicillin, 77% to piperacillin, 64% to cephalothin, 60% to ampicillin/sulbactam, 59% to cefoperazone, 57% to cefazolin, 55% to cefuroxime, 51% to TMP-SMZ, 51% to tobramycin, 50% to gentamicin, 49% to aztreonam, cefetaxime and ceftriaxone respectively, 47% to ceftazidime, 47% to cefepime, 46% to ciprofloxacin, 46% to ticarcillin/clavulanate, 44% to amikacin, 38% to cefoxitin, 22% to piperacillin/tazobactam, while all strains were tested susceptible to imipenem.</p><p><b>CONCLUSIONS</b>Prior receipt of amtimicrobial therapy was significantly associated with infection caused by a resistant organism and most strains were resistant to multiple antibiotics.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Infecciones por Klebsiella
/
Epidemiología
/
Factores de Riesgo
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Farmacorresistencia Bacteriana
/
Quimioterapia
/
Klebsiella pneumoniae
Tipo de estudio:
Estudio de etiología
/
Estudio observacional
/
Factores de riesgo
/
Estudio de tamizaje
Límite:
Adolescente
/
Adulto
/
Anciano
/
Aged80
/
Niño
/
Child, preschool
/
Femenino
/
Humanos
/
Lactante
/
Masculino
Idioma:
Inglés
Revista:
Chinese Medical Journal
Año:
2002
Tipo del documento:
Artículo
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