Inflammatory reaction and alterations of pulmonary surfactant in Pseudomonas Aeruginosa pneumonia in immunocompromised rats / 中华医学杂志(英文版)
Chinese Medical Journal
; (24): 1099-1100, 2002.
Article
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| WPRIM
| ID: wpr-340375
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WPRO
ABSTRACT
Pulmonary surfactant ( PS ) compromises lipids and surfactant proteins (SP) and lines on the alveolar air-liquid interface. It can reduce surface tension, prevent alveoli from collapse and reduce alveoli edema by disaturated dipalmitoylphosphatidylcholine. It also modulates the pulmonary immunology by SP-A and SP-D. In this study,we established a rat model of immunocompromised host (ICH) with pulmonary infection of Pseudomonas aeruginosa (P. aeruginosa), then studied its pulmonary inflammatory reaction and analyzed the concentration of lipids and SP-A in bronchoalveolar lavage fluid (BALF) during infection.
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Índice:
WPRIM
Asunto principal:
Fisiología
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Proteolípidos
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Infecciones por Pseudomonas
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Surfactantes Pulmonares
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Líquido del Lavado Bronquioalveolar
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Química
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Ratas Sprague-Dawley
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Neumonía Bacteriana
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Proteína A Asociada a Surfactante Pulmonar
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Proteínas Asociadas a Surfactante Pulmonar
Límite:
Animals
Idioma:
En
Revista:
Chinese Medical Journal
Año:
2002
Tipo del documento:
Article