Dyspnea as a Prognostic Factor in Patients with Non-Small Cell Lung Cancer
Yonsei Medical Journal
;
: 1063-1069, 2016.
Artículo
en Inglés
| WPRIM
| ID: wpr-34060
ABSTRACT
PURPOSE:
To investigate associations between dyspnea and clinical outcomes in patients with non-small cell lung cancer (NSCLC). MATERIALS ANDMETHODS:
From 2001 to 2014, we retrospectively reviewed the prospective lung cancer database of St. Paul's Hospital at the Catholic University of Korea. We enrolled patients with NSCLC and evaluated symptoms of dyspnea using modified Medical Research Council (mMRC) scores. Also, we estimated pulmonary functions and analyzed survival data.RESULTS:
In total, 457 NSCLC patients were enrolled, and 259 (56.7%) had dyspnea. Among those with dyspnea and whose mMRC scores were available (109 patients had no mMRC score), 85 (56.6%) patients had an mMRC score <2, while 65 (43.3%) had an mMRC score ≥2. Significant decreased pulmonary functions were observed in patients with dyspnea. In multivariate analysis, aging, poor performance status, advanced stage, low forced expiratory volume in 1 second (%), and an mMRC score ≥2 were found to be significant prognostic factors for patient survival.CONCLUSION:
Dyspnea could be a significant prognostic factor in patients with NSCLC.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Pronóstico
/
Índice de Severidad de la Enfermedad
/
Volumen Espiratorio Forzado
/
Estudios Retrospectivos
/
Carcinoma de Pulmón de Células no Pequeñas
/
Disnea
/
Neoplasias Pulmonares
/
Estadificación de Neoplasias
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
Límite:
Anciano
/
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Yonsei Medical Journal
Año:
2016
Tipo del documento:
Artículo
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