Effect of laparoscopic surgery on the immune function of patients with endometriosis / 南方医科大学学报
Journal of Southern Medical University
;
(12): 1463-1465, 2008.
Artículo
en Chino
| WPRIM
| ID: wpr-340793
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the effect of laparoscopic surgery on the immune function of patients with endometriosis.</p><p><b>METHOD</b>Blood samples were obtained from 36 patients undergoing laparoscopy for endometriosis before and 1 day and 3 days after the operation. Peripheral blood T-cell subsets CD3, CD4, and CD8 were determined with flow cytometry, the levels of IgM, IgG, IgA, Complement (C)3, C4, C-reactive protein and (CRP) were detected with turbidimetry, and the levels of interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) were measured with enzyme linked immunosorbent assay (ELISA).</p><p><b>RESULTS</b>No significant variation were found in the T-cell subsets, IgM, IgA, C4 after the operation (P>0.05). The levels of IgG and C3 1 day after the operation were significantly lower than the preoperative levels (P<0.05) and nearly recovered the preoperative level 3 days after operation. Serum concentration of IL-6, TNF-alpha, and CRP 1 day after the operation were significantly higher than the preoperative levels (P<0.01) and decreased 3 days after the operation.</p><p><b>CONCLUSIONS</b>The immune function of patients with endometriosis is mildly affected by laparoscopic surgery and recover rapidly, which may be one of the reasons for quick recovery of patients after laparoscopy for endometriosis.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Cirugía General
/
Sangre
/
Proteína C-Reactiva
/
Complemento C3
/
Inmunoglobulina G
/
Ensayo de Inmunoadsorción Enzimática
/
Antígenos CD4
/
Subgrupos de Linfocitos T
/
Interleucina-6
/
Factor de Necrosis Tumoral alfa
Límite:
Adulto
/
Femenino
/
Humanos
Idioma:
Chino
Revista:
Journal of Southern Medical University
Año:
2008
Tipo del documento:
Artículo
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