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A Case of Sunitinib-Associated Thrombotic Thrombocytopenic Purpura / 대한내과학회지
Korean Journal of Medicine ; : 303-307, 2013.
Artículo en Coreano | WPRIM | ID: wpr-34182
ABSTRACT
Thrombotic thrombocytopenic purpura and hemolytic uremic syndrome (TTP-HUS) is an acute condition with abnormalities of multiple organ systems. It is characterized by microangiopathic hemolytic anemia and thrombocytopenia. Several chemotherapeutic agents have been implicated in causing TTP-HUS. We report a case of TTP-HUS during treatment with sunitinib in a patient with metastatic renal cell carcinoma. A 53-year-old woman visited our hospital for fever and cough. She was diagnosed with sunitinib-induced TTP. Discontinuation of sunitinib and plasmapheresis improved her TTP. When she experienced disease progression after a prolonged period without treatment, sorafenib was tried, resulting in a partial response without recurrence of TTP-HUS.
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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Compuestos de Fenilurea / Púrpura Trombocitopénica Trombótica / Pirroles / Recurrencia / Trombocitopenia / Nucleótidos de Timina / Carcinoma de Células Renales / Plasmaféresis / Niacinamida / Progresión de la Enfermedad Límite: Femenino / Humanos Idioma: Coreano Revista: Korean Journal of Medicine Año: 2013 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Compuestos de Fenilurea / Púrpura Trombocitopénica Trombótica / Pirroles / Recurrencia / Trombocitopenia / Nucleótidos de Timina / Carcinoma de Células Renales / Plasmaféresis / Niacinamida / Progresión de la Enfermedad Límite: Femenino / Humanos Idioma: Coreano Revista: Korean Journal of Medicine Año: 2013 Tipo del documento: Artículo