Clinical characteristics and results of cervical spinal cord injury in the patients with ossification of the posterior longitudinal ligament / 中华外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the clinical characteristics and results of cervical spinal cord injury (SCI) in the patients with ossification of the posterior longitudinal ligament (OPLL).</p><p><b>METHODS</b>Nineteen patients with cervical SCI associated with OPLL were retrospectively analyzed. Data collection included pre- and postoperative neurological function, OPLL-type, MRI signal changes and surgical approaches.</p><p><b>RESULTS</b>Spinal cord associated with OPLL was injured severely by mild trauma. Methylprednisolone sodium succinate was used within 8 h after trauma in 12 cases. Two of them died of complications. The neurological functions were markedly improved in the other 10 cases. Seventeen cases had surgical treatment. The neurological functions (Frankel grade) were improved significantly in the operated patients except for one, who died 27 d after operation.</p><p><b>CONCLUSIONS</b>The patients with OPLL are prone to have severe SCI, which directly associates with the preexisting OPLL-type and hyper-intensity signal change in the spinal cord on MRI. Both of using methylprednisolone sodium succinate administration within 8 h after trauma and surgical decompression may improve the neurological outcomes.</p>