Prevalence of HBV Genotypes in Korean Patients with Chronic Hepatitis B / 대한간학회지
The Korean Journal of Hepatology
;
: 381-386, 2001.
Artículo
en Coreano
| WPRIM
| ID: wpr-34247
ABSTRACT
BACKGROUND/AIMS:
Hepatitis B virus (HBV) genotypes have distinct geographic distributions. The possibility of pathogenic differences among HBV genotypes has been suggested. We investigated the prevalence of HBV genotypes in Korea and the association between distinct genotypes and clinical outcomes.METHODS:
Using a PCR-RFLP and sequencing, HBV genotypes were determined in 136 patients with chronic type B hepatitis.RESULTS:
The genotype C was detected in 131 patients (96.3%), and other 5 patients (3.7%) had genotype B. There were no significant differences in sex, age, disease duration, ALT level, HBeAg/anti-HBe status, or HBeAg loss between genotype B and C patients.CONCLUSIONS:
These results suggest that almost all patients with chronic hepatitis B are infected with genotype C. Genotypes do not influence the outcome of chronic hepatitis B patients in Korea.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Virus de la Hepatitis B
/
Epidemiología
/
Prevalencia
/
Hepatitis B Crónica
/
Genotipo
/
Hepatitis
/
Antígenos e de la Hepatitis B
/
Hepatitis Crónica
/
Corea (Geográfico)
Tipo de estudio:
Estudio de prevalencia
Límite:
Humanos
País/Región como asunto:
Asia
Idioma:
Coreano
Revista:
The Korean Journal of Hepatology
Año:
2001
Tipo del documento:
Artículo
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