Reprogramming in origin and development of leukemia stem/progenitor cells / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 1123-1126, 2009.
Artículo
en Chino
| WPRIM
| ID: wpr-343335
ABSTRACT
The success of yielding induced pluripotent stem (iPS) cells from human somatic cells demonstrates the important role of reprogramming in the formation of stem/progenitor cells and initiates the exploration of the origin of leukemia stem cells. In our previous work, we have found two types of leukemia, bona fide leukemia and non-bona fide leukemia. Different leukemias originate from different leukemia stem/progenitor cells which are critical to the genesis and evolution of leukemia. Bona fide leukemia and non-bona fide leukemia originate from leukemia stem cells and progenitor cells, respectively. Recent research suggests that different types of leukemia are influenced by the reprogramming state of their origin cells.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Células Madre
/
Células Madre Neoplásicas
/
Leucemia
/
Diferenciación Celular
/
Reprogramación Celular
/
Células Madre Pluripotentes Inducidas
/
Genética
Límite:
Humanos
Idioma:
Chino
Revista:
Journal of Experimental Hematology
Año:
2009
Tipo del documento:
Artículo
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