Effect of microneedle combined with Lauromacrogol on skin capillary network: experimental study / 中华整形外科杂志
Chinese Journal of Plastic Surgery
;
(6): 448-451, 2014.
Artículo
en Chino
| WPRIM
| ID: wpr-343414
ABSTRACT
<p><b>OBJECTIVE</b>To explore the effect of microneedle combined with Lauromacrogol on skin capillary network.</p><p><b>METHODS</b>24 male Leghone (1.5-2.0 kg in weight) were randomly divided into three groups as group A (microneedle combined with Lauromacrogol), B (microneedle combined with physiological saline) , and C(control). The cockscombs were treated. The specimens were taken on the 7th, 14th, 21th , and 28th day postoperatively. HE staining, immunohistochemical staining and special staining were performed for study of the number of capillary and collagen I/III , as well as elastic fibers.</p><p><b>RESULTS</b>The color of cockscombs in group A became lightening after treatment. The number of capillary decreased as showing by HE staining. The collagen I and III in group B was significantly different from that in group A and C (P < 0.05). Special staining showed proliferation of elastic fibers in group B.</p><p><b>CONCLUSIONS</b>It indicates that microneedle combined with Lauromacrogol could effectively reduce the capillary in cockscomb without any tissue fibrosis. Microneedle can stimulate the proliferation of elastic fiber, so as to improve the skin ageing process.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Farmacología
/
Polietilenglicoles
/
Capilares
/
Punciones
/
Distribución Aleatoria
/
Envejecimiento de la Piel
/
Pollos
/
Cresta y Barbas
/
Métodos
/
Agujas
Límite:
Animales
Idioma:
Chino
Revista:
Chinese Journal of Plastic Surgery
Año:
2014
Tipo del documento:
Artículo
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