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Expression of human epididymis protein 2beta1 in the testis and epididymis of adolescent male rats / 中华男科学杂志
National Journal of Andrology ; (12): 780-783, 2006.
Artículo en Chino | WPRIM | ID: wpr-343525
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the expression of human epididymal secretary protein 2 isoform human epididymal protein 2beta1(HE2beta1) in the testis and epididymis of adolescent male rats along with its significance.</p><p><b>METHODS</b>Immunohistochemical staining was used to detect the expression and localization of HE2beta1 in the testis and epididymis of 15 adolescent SD rats.</p><p><b>RESULTS</b>HE2beta1 immunoreactive staining was detected in the testis and epididymis. In the epithelia of the epididymal duct, HE2beta1 expressed mainly in the supranuclear region of the principle cells and the basement membrane of some epithelial cells; there were no immunostaining in the n clear cells, halo cells and basal cells. The immunopositive reaction was detected, weak in the distal caput, strong in the proximal, middle corpus and the cauda, but negative in the initial segment. Immunopositive results of HE2beta1 were also observed in some of the nuclei of spermatogonia and Sertoli cells with negatively-stained cytoplasm.</p><p><b>CONCLUSION</b>Immunohistochemical staining is a fairly sensitive method for detecting HE2beta1 expression. The localization and expression level of HE2beta1 in the genital duct of adolescent male rats exhibited a region- and cell-specific expression pattern, which suggests that HE2beta1 may play an important role in spermatogenesis, maturation and epididymal epithelial innate defense mechanisms.</p>
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Testículo / Inmunohistoquímica / Glicopéptidos / Ratas Sprague-Dawley / Epidídimo / Células Intersticiales del Testículo / Metabolismo / Antígenos de Superficie Límite: Animales / Humanos / Masculino Idioma: Chino Revista: National Journal of Andrology Año: 2006 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Testículo / Inmunohistoquímica / Glicopéptidos / Ratas Sprague-Dawley / Epidídimo / Células Intersticiales del Testículo / Metabolismo / Antígenos de Superficie Límite: Animales / Humanos / Masculino Idioma: Chino Revista: National Journal of Andrology Año: 2006 Tipo del documento: Artículo