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Analysis of recurrence and prognosis after surgical resection for I stage lower rectal carcinoma / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery ; (12): 117-120, 2006.
Artículo en Chino | WPRIM | ID: wpr-345118
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the clinicopathologic factors related with recurrence and prognosis after surgical resection for I stage lower rectal carcinoma.</p><p><b>METHODS</b>The related clinicopathologic factors for recurrence and prognosis of 166 patients with I stage lower rectal carcinoma after surgical resection were retrospectively analyzed using univariate and multivariate methods.</p><p><b>RESULTS</b>A total of 138 patients with I stage lower rectal carcinoma received radical resection according to the operative rules of total mesorectal excision (TME). Ninety-three patients received abdominoperineal resection (APR) operation, 45 patients received sphincter preserving operation, and 28 patients received local excision. The local recurrence rates were 6.5% (6/93), 2.2% (1/45), 17.9% (5/28), respectively . Histological differentiation and operative procedures were associated with local recurrence. The 5-year survival rates were 91.1% in APR group, 95.5% in sphincter preservation group and 82.6% in local resection group. Univariate analysis revealed that histological differentiation and local recurrence were correlated with prognosis. Multivariate analysis revealed that local recurrence was the most important prognostic factor for I stage lower rectal carcinoma.</p><p><b>CONCLUSIONS</b>Radical resection of I stage lower rectal carcinoma has low recurrence rate and better prognosis. Sphincter preserving operation and local excision must be strictly selected in proper patients.</p>
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Patología / Pronóstico / Neoplasias del Recto / Cirugía General / Estudios Retrospectivos / Resultado del Tratamiento / Radioterapia Adyuvante / Recurrencia Local de Neoplasia / Estadificación de Neoplasias Tipo de estudio: Estudio observacional / Estudio pronóstico Límite: Adulto / Anciano / Aged80 / Femenino / Humanos / Masculino Idioma: Chino Revista: Chinese Journal of Gastrointestinal Surgery Año: 2006 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Patología / Pronóstico / Neoplasias del Recto / Cirugía General / Estudios Retrospectivos / Resultado del Tratamiento / Radioterapia Adyuvante / Recurrencia Local de Neoplasia / Estadificación de Neoplasias Tipo de estudio: Estudio observacional / Estudio pronóstico Límite: Adulto / Anciano / Aged80 / Femenino / Humanos / Masculino Idioma: Chino Revista: Chinese Journal of Gastrointestinal Surgery Año: 2006 Tipo del documento: Artículo