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The prognostic impact of perioperative blood transfusion on survival in patients with bladder urothelial carcinoma treated with radical cystectomy
Korean Journal of Urology ; : 295-304, 2015.
Artículo en Inglés | WPRIM | ID: wpr-34598
ABSTRACT

PURPOSE:

The aim of our study was to assess the influence of perioperative blood transfusion (PBT) on survival outcomes following radical cystectomy (RC) and pelvic lymph node dissection (PLND). MATERIALS AND

METHODS:

We reviewed and analyzed the clinical data of 432 patients who underwent RC for bladder cancer from 1991 to 2012. PBT was defined as the transfusion of allogeneic red blood cells during RC or postoperative hospitalization.

RESULTS:

Of all patients, 315 patients (72.9%) received PBT. On multivariate logistic regression analysis, female gender (p=0.015), a lower preoperative hemoglobin level (p=0.003), estimated blood loss>800 mL (p4 packed red blood cell units was an independent predictor of overall survival (p=0.007), but not in cancer specific survival.

CONCLUSIONS:

Our study was not conclusive to detect a clear association between PBT and survival after RC. However, the efforts should be made to continue limiting the overuse of transfusion especially in patients who are expected to have a high probability of PBT, such as females and those with a low preoperative hemoglobin level and history of neoadjuvant chemotherapy.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Pelvis / Pronóstico / Vejiga Urinaria / Neoplasias de la Vejiga Urinaria / Transfusión Sanguínea / Carcinoma de Células Transicionales / Estudios Retrospectivos / Factores de Riesgo / Resultado del Tratamiento / Supervivencia sin Enfermedad Tipo de estudio: Estudio de etiología / Estudio observacional / Estudio pronóstico / Factores de riesgo Límite: Anciano / Femenino / Humanos / Masculino País/Región como asunto: Asia Idioma: Inglés Revista: Korean Journal of Urology Año: 2015 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Pelvis / Pronóstico / Vejiga Urinaria / Neoplasias de la Vejiga Urinaria / Transfusión Sanguínea / Carcinoma de Células Transicionales / Estudios Retrospectivos / Factores de Riesgo / Resultado del Tratamiento / Supervivencia sin Enfermedad Tipo de estudio: Estudio de etiología / Estudio observacional / Estudio pronóstico / Factores de riesgo Límite: Anciano / Femenino / Humanos / Masculino País/Región como asunto: Asia Idioma: Inglés Revista: Korean Journal of Urology Año: 2015 Tipo del documento: Artículo