Study on the biofilm early formation of Streptococcus mutans luxS gene mutation / 中华口腔医学杂志
Chinese Journal of Stomatology
;
(12): 72-75, 2009.
Artículo
en Chino
| WPRIM
| ID: wpr-346754
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the effect of Streptococcus mutans luxS mutarotation on the early biofilm formation.</p><p><b>METHODS</b>Based on the immobilization of magnetic beads by adherent cells, an assay of biofilm quantitative analysis was developed for the kinetic quantification of biofilm formation in this study. Streptococcus mutans luxS mutant strain was constructed and subject to this biofilm luxS mutant strain were compared.</p><p><b>RESULTS</b>The delta luxS mutant started to form a biofilm from the 6th hour (delta BFI = 2.015), and the delta BFI of luxS mutant increased more quickly than that of the wild type strain, until reaching a complete immobilization of the beads after 10 hours (delta BFI = 7.025). The wild-type strain start to form a biofilm from the 10 th hour (delta BFI = 1.875) and the beads were completely immobilized between 12 and 14 hours.</p><p><b>CONCLUSIONS</b>The luxS mutation can accelerate biofilm on a polystyrene surface during the mid-exponential growth phase. And a luxS-dependent signal may play an important role in the early biofilm formation of Streptococcus mutans.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Streptococcus mutans
/
Liasas de Carbono-Azufre
/
Proteínas Bacterianas
/
Regulación Bacteriana de la Expresión Génica
/
Eliminación de Gen
/
Biopelículas
/
Genética
Idioma:
Chino
Revista:
Chinese Journal of Stomatology
Año:
2009
Tipo del documento:
Artículo
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