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Relationship of concentration of lactoferrin and lysozyme in saliva and dental caries in primary dentition / 中华口腔医学杂志
Chinese Journal of Stomatology ; (12): 82-84, 2009.
Artículo en Chino | WPRIM | ID: wpr-346766
ABSTRACT
<p><b>OBJECTIVE</b>To explore the relationship between the concentrations of lactoferrin and lysozyme in saliva and dental caries in primary dentition among Chinese children.</p><p><b>METHODS</b>Forty children with high dmft score (dmft > or = 5) and 40 caries-free children (dmft = 0) were sampled and assigned into two groups. Total salivary proteins was measured by means of bicinchoninic acid. Sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) was performed to analyze the images of target straps. Lactoferrin and lysozyme were detected using Western blotting method.</p><p><b>RESULTS</b>The total salivary protein in high dmft group [(852.02 +/- 206.14) mg/L] was lower than that of caries-free group [(1032.44 +/- 221.99) mg/L, P < 0.001]. The ratio of 77,000 protein in high dmft group [(12.50 +/- 7.73) IA/microg] was significantly higher than that of the caries-free children [(8.71 +/- 4.28) IA/microg, P = 0.009], while there was no significant difference for 14,500 protein between them (P = 0.137). The ratio of lactoferrin was higher in high dmft group [(229.04 +/- 197.14) IA/microg] than that in caries-free children [(144.07 +/- 99.91) IA/microg, P = 0.018], while no significant difference for lysozyme between the two groups (P = 0.091).</p><p><b>CONCLUSIONS</b>Saliva protein is closely related to caries in primary dentition. Lactoferrin may be one of the important components.</p>
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Saliva / Proteínas y Péptidos Salivales / Diente Primario / Muramidasa / Estudios de Casos y Controles / Química / Epidemiología / Prevalencia / Caries Dental / Lactoferrina Tipo de estudio: Estudio observacional / Estudio de prevalencia / Factores de riesgo Límite: Child, preschool / Femenino / Humanos / Masculino Idioma: Chino Revista: Chinese Journal of Stomatology Año: 2009 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Saliva / Proteínas y Péptidos Salivales / Diente Primario / Muramidasa / Estudios de Casos y Controles / Química / Epidemiología / Prevalencia / Caries Dental / Lactoferrina Tipo de estudio: Estudio observacional / Estudio de prevalencia / Factores de riesgo Límite: Child, preschool / Femenino / Humanos / Masculino Idioma: Chino Revista: Chinese Journal of Stomatology Año: 2009 Tipo del documento: Artículo