Advance in studies on effect of paeoniflorin on nervous system / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 297-301, 2013.
Artículo
en Chino
| WPRIM
| ID: wpr-346829
ABSTRACT
Paeoniflorin (PF) is the chief active component of paeonia, with diverse pharmacological actions and wide application. Recently, the effect of PF on nervous system has attracted increasingly more attention. According to current study findings, PF can ameliorate the decline of memory and learning capacities in many dementia model animals, and have effect in protecting the cerebral ischemia injury, treating Parkinson's disease, reliving pain and improving neural synapse plasticity. Thought its mechanism has not been clarified, current findings show that adenosine A1 receptor plays an important role, while M cholinergic receptor, opiate receptor, calcium ion channel and NF-KB may also play a part in paeoniflorin's effect on nervous system.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Farmacología
/
Benzoatos
/
Hidrocarburos Aromáticos con Puentes
/
Canales de Calcio
/
FN-kappa B
/
Monoterpenos
/
Receptor de Adenosina A1
/
Glucósidos
/
Aprendizaje
/
Memoria
Tipo de estudio:
Estudio pronóstico
Límite:
Animales
Idioma:
Chino
Revista:
China Journal of Chinese Materia Medica
Año:
2013
Tipo del documento:
Artículo
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