Studies on metabolism of total terpene ketones from Swertia mussotii with human intestinal bacteria / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 3743-3747, 2012.
Artículo
en Chino
| WPRIM
| ID: wpr-346846
ABSTRACT
<p><b>OBJECTIVE</b>To study the metabolism of total terpene ketones from Swertia mussotii with human intestinal bacteria.</p><p><b>METHOD</b>Total terpene ketones were incubated with human intestinal bacteria under an anaerobic environment and at 37 degrees C. The metabolites were extracted by ethyl acetate processing, detected by HPLC-DAD method. A qualitative analysis was made for its metabolites by HPLC-MS.</p><p><b>RESULT</b>Eight metabolites were detected from total terpene ketones from S. mussotii with human intestinal bacteria, and two of them were preliminarily identified as gentianine and mangiferin aglycon.</p><p><b>CONCLUSION</b>Total terpene ketones can be metabolized with human intestinal bacteria, which provides basis for experiments on the metabolism process total terpene ketones from S. mussotii with human intestinal bacteria.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Espectrometría de Masas
/
Terpenos
/
Bacterias
/
Cromatografía Líquida de Alta Presión
/
Swertia
/
Xantonas
/
Alcaloides
/
Anaerobiosis
/
Intestinos
/
Cetonas
Tipo de estudio:
Investigación cualitativa
Límite:
Humanos
Idioma:
Chino
Revista:
China Journal of Chinese Materia Medica
Año:
2012
Tipo del documento:
Artículo
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