Lactone constituents of Saussurea involucrata / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the chemical constituents of Saussurea involucrata.</p><p><b>METHOD</b>Compounds were isolated and purified by column chromatography, and their structures were elucidated by chemical and spectroscopic methods.</p><p><b>RESULT</b>Eight compounds were yielded and identified as beta-sitosterol (1), dotriacontanoic acid (2), hexacosan-4-olide (3), (+)-11alpha, 13-dihydrodehydrocostuslactone (4), 8alpha-acetoxydehydrocostus lactone (5), zaluzanin C (6), 11,13beta-dihydrozaluzanin C (7), 8alpha-hydroxy-11beta-11,13-dihydrodehydrocostuslactone (8).</p><p><b>CONCLUSION</b>Compounds 2-7 were first isolated from S. involucrate.</p>