Isoflavones from vines of Pueraria lobata / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the isoflavones from the vines of Pueraria lobata.</p><p><b>METHOD</b>The compounds were isolated by column chromatography over silica gel and RP-C18, and purified by Sephadex LH-20 column chromatography and preparative TLC. The structures were elucidated on the basis of physico-chemical properties and spectral data.</p><p><b>RESULT</b>Twelve compounds were isolated and identified as 3'-methoxydaidzein (1), formononetin (2), genistein (3), daidzein (4), daidzin (5), genistin (6), ononin (7), 5-hydroxyl ononin (8), calycosin (9), 6"-O-acetyl genistein (10), 6"-O-acetyl daidzin (11), puerarin (12).</p><p><b>CONCLUSION</b>For the first time, compounds 9-11 were isolated from the genus Pueraria plant, and compounds 1, 3, 6-8 were obtained from the vines of this plant.</p>