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Neuroimaging of Hemichorea-Hemiballism
Journal of the Korean Neurological Association ; : 318-323, 2007.
Artículo en Coreano | WPRIM | ID: wpr-34780
ABSTRACT

BACKGROUND:

Hemichorea-Hemiballism (HCHB) can be caused by various diseases such as cerebrovascular disease, hyperglycemia, tumor, and inflammatory diseases. However, there are a few case studies using functional imaging such as single photon emission computed tomography (SPECT).

METHODS:

In this study, we included patients with HCHB. The patients with hyperglycemia over 250 mg/dl or high signal intensity on T1 weighted imaging were excluded. Clinical and neuroimaging characteristics of the patients were obtained and analyzed.

RESULTS:

We included 20 patients (MF=128, mean age=67.1+/-15.3). Sixteen patients were presented with hemiballism and four with hemichorea. Six patients had no structural lesions causing HCHB. Subthalamic nucleus was the causative lesion in 6 patients. Other lesions associated with HCHB were basal ganglia, thalamus, and cortices. In a patient without structural lesion, anti-double stranded DNA antibody was detected. Brain SPECT showed not only perfusion abnormalities in the cases without structural lesions but also additional abnormalities in those with definite lesions.

CONCLUSIONS:

Various mechanisms were related to the development of HCHB. Functional imaging such as SPECT and immunological work-up is needed to investigate the underlying pathomechanism of HCHB.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Perfusión / Tálamo / Ganglios Basales / Encéfalo / ADN / Tomografía Computarizada de Emisión de Fotón Único / Núcleo Subtalámico / Discinesias / Neuroimagen / Hiperglucemia Límite: Humanos Idioma: Coreano Revista: Journal of the Korean Neurological Association Año: 2007 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Perfusión / Tálamo / Ganglios Basales / Encéfalo / ADN / Tomografía Computarizada de Emisión de Fotón Único / Núcleo Subtalámico / Discinesias / Neuroimagen / Hiperglucemia Límite: Humanos Idioma: Coreano Revista: Journal of the Korean Neurological Association Año: 2007 Tipo del documento: Artículo