Contents of serum Cyst-C and urinary microalbumin in children with Henoch-Schonlein purpura / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 346-348, 2009.
Artículo
en Chino
| WPRIM
| ID: wpr-347919
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the clinical significance of serum Cyst-C and urinary microalbumin in early renal impairment in children with Henoch-Schonlein purpura (HSP).</p><p><b>METHODS</b>Forty-eight children with HSP and who had normal serum creatinine level and 31 healthy children were enrolled. Contents of serum Cyst-C and urinary microalbumin were measured using ELISA and immunoturbidimetry, respectively. Urinary routine examination was performed in children with HSP. The contents of serum Cyst-C and urinary microalbumin were re-examined one month after treatment (recovery phase).</p><p><b>RESULTS</b>The contents of serum Cyst-C (2.24+/- 0.81 mg/L) and urinary microalbumin (20.04+/- 10.32 mg/L) in the HSP group at the acute phase were significantly higher than those in the control (0.85+/- 0.20 and 2.30+/- 1.38 mg/L respectively; P< 0.01). Serum Cyst-C (1.70+/- 0.30 mg/L) and urinary microalbumin contents (13.20+/- 8.16 mg/L) were significantly reduced at the recovery phase compared with those at the acute phase in the HSP group (P< 0.01). The proportion of urinary routine abnormality (33.3%) was significantly lower than that of urinary microalbumin (68.8%) and serum Cyst-C abnormalities (72.9%) in the HSP group (P< 0.01).</p><p><b>CONCLUSIONS</b>Serum Cyst-C and urinary microalbumin may serve as indexes in the assessment of early renal impairment in children with HSP.</p>
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Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Vasculitis por IgA
/
Orina
/
Sangre
/
Creatina
/
Diagnóstico
/
Albuminuria
/
Cistatina C
/
Tasa de Filtración Glomerular
/
Enfermedades Renales
Tipo de estudio:
Estudio diagnóstico
Límite:
Adolescente
/
Niño
/
Child, preschool
/
Femenino
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
Chinese Journal of Contemporary Pediatrics
Año:
2009
Tipo del documento:
Artículo
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