Study on the clinical use of alpha-fetoprotein (AFP) colloidal gold diagnostic strip / 中华流行病学杂志
Chinese Journal of Epidemiology
;
(12): 210-212, 2003.
Artículo
en Chino
| WPRIM
| ID: wpr-348877
ABSTRACT
<p><b>OBJECTIVE</b>To test the sensitivity and specificity of alpha-fetoprotein (AFP) colloidal gold diagnostic strip as compared with RIA-AFP diagnostic kit.</p><p><b>METHODS</b>Double blind method was used to test sera from 426 healthy people and 1567 patients selected in two general hospitals and a cancer hospital. Each serum was measured by RIA-AFP and AFP colloidal gold diagnostic strip on the same day. RIA-AFP diagnostic results was identified as true positive or negative.</p><p><b>RESULTS</b>Among 426 healthy people, all the RIA-AFP test showed negative result (serum AFP concentration less than 25 IU/ml), but the AFP colloidal gold diagnostic strip had 1.88% false positive. When comparing the result from 1567 patients measured by RIA-AFP, the sensitivity and specificity of AFP colloidal gold diagnostic strip were 99.3%, and 97.2%, respectively. The crude correspondence rate between the two diagnostic regents was 97.6%.</p><p><b>CONCLUSION</b>AFP colloidal gold diagnostic strip showed very good result and could be used as a screening diagnostic kit in clinic and hospital settings.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Juego de Reactivos para Diagnóstico
/
Sangre
/
Radioinmunoensayo
/
Alfa-Fetoproteínas
/
Biomarcadores de Tumor
/
Método Doble Ciego
/
Reproducibilidad de los Resultados
/
Sensibilidad y Especificidad
/
Oro Coloide
/
Carcinoma Hepatocelular
Tipo de estudio:
Ensayo Clínico Controlado
/
Estudio diagnóstico
/
Estudio pronóstico
Límite:
Humanos
Idioma:
Chino
Revista:
Chinese Journal of Epidemiology
Año:
2003
Tipo del documento:
Artículo
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