Multidrug resistance-associated proteins and their roles in multidrug resistance / 药学学报
Acta Pharmaceutica Sinica
;
(12): 479-486, 2011.
Artículo
en Chino
| WPRIM
| ID: wpr-348931
ABSTRACT
Multidrug resistance (MDR) is a major impediment to the success of cancer chemotherapy. Multidrug resistance-associated proteins (MRPs) play an important role in the process of MDR. As an ATP-binding cassette (ABC) transporter superfamily, MRPs are selective and specific drug efflux pumps. In this paper, physiological characteristics, structural characteristics and resistance profile of MRPs and the associated reversal studies are reviewed.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Farmacología
/
Fisiología
/
Química
/
Resistencia a Múltiples Medicamentos
/
Resistencia a Antineoplásicos
/
Proteínas Asociadas a Resistencia a Múltiples Medicamentos
/
Quimioterapia
/
Metabolismo
/
Neoplasias
/
Antineoplásicos
Límite:
Humanos
Idioma:
Chino
Revista:
Acta Pharmaceutica Sinica
Año:
2011
Tipo del documento:
Artículo
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