Effects of different concentration extract from shenghua decoction on contractile activity of the uterine smooth muscle isolated from normal, estrogen-treated and postpartum mice / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 243-246, 2006.
Artículo
en Chino
| WPRIM
| ID: wpr-350963
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the effects of different concentration extract from Shenghua decoction on contractile activity of the uterine smooth muscle isolated from normal, estrogen-treated and postpartum mice.</p><p><b>METHOD</b>Medlab/4 s vital signal recorder was used to measure the effects of extract from Shenghua decoction (3-12 mg x mL(-1)) on contractile amplitude and frequency of the isolated uterus from normal, estrogen-treated and postpartum mice.</p><p><b>RESULT</b>Shenghua decoction extract (3-12 mg x mL(-1)) significantly decreased the contractile activity of the mouse isolated uterus in normal non-pregnancy and postpartum, but significantly increased that of the mouse isolated uterus treated with estrogen, and didn't show significant concentration-response relationship.</p><p><b>CONCLUSION</b>The effects of Shenghua decoction extract on contractile activity of mouse-isolated uterus treated with estrogen cannot represent the pharmacological effects on that of in normal non-pregnancy and postpartum uterus.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Farmacología
/
Plantas Medicinales
/
Contracción Uterina
/
Útero
/
Técnicas In Vitro
/
Medicamentos Herbarios Chinos
/
Química
/
Angelica sinensis
/
Periodo Posparto
/
Relación Dosis-Respuesta a Droga
Límite:
Animales
Idioma:
Chino
Revista:
China Journal of Chinese Materia Medica
Año:
2006
Tipo del documento:
Artículo
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