Study on the water-soluble composition release of compound Danshen sustained-release tablet / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study on the release of compound Danshen sustained-release tablet and the evaluate method of Chinese material medica compound sustained-release preparation.</p><p><b>METHOD</b>Rotating basket method and HPLC were employed.</p><p><b>RESULT</b>Through the determination of 6 time-point samples, the water-soluble compositions of compound Danshen sustained-release tablet had a Well-balanced release behavior with a zero-grade release model or Higuchi release model.</p><p><b>CONCLUSION</b>Compound Danshen sustained-release tablet had a zero-grade release model. The method was rapid and stable and could be applied to evaluate the water-soluble composition release of compound Danshen sustained-release Tablet.</p>