Acute Lymphoblastic Leukemia in Elderly Patients: A Single Institution's Experience
The Korean Journal of Internal Medicine
;
: 328-339, 2011.
Artículo
en Inglés
| WPRIM
| ID: wpr-35155
ABSTRACT
BACKGROUND/AIMS:
We investigated the clinical characteristics and prognosis of elderly patients with acute lymphoblastic leukemia (ALL).METHODS:
We reviewed the clinical data, laboratory findings, bone marrow findings, and cytogenetic analysis of elderly patients (> or = 60 years) with ALL, and data of an additional 101 younger adult patients ( or = 60 years) and 101 younger adult patients ( or = 60 years) was 10.3 months (p = 0.003). In the elderly patients with ALL, T cell lineage and the presence of lymphadenopathy were significant prognostic factors for OS in a univariate analysis (p = 0.033 and 0.041, respectively).CONCLUSIONS:
The outcomes of Korean elderly patients with ALL were poor, and the shorter OS was mainly due to the low CR rate. T-cell lineage and the presence of lymphadenopathy were significant prognostic factors in Korean elderly patients with ALL.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Factores de Tiempo
/
Examen de la Médula Ósea
/
Inducción de Remisión
/
Cromosoma Filadelfia
/
Distribución de Chi-Cuadrado
/
Modelos Logísticos
/
Modelos de Riesgos Proporcionales
/
Tasa de Supervivencia
/
Estudios Retrospectivos
/
Factores de Riesgo
Tipo de estudio:
Estudio de etiología
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Adolescente
/
Adulto
/
Anciano
/
Aged80
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
The Korean Journal of Internal Medicine
Año:
2011
Tipo del documento:
Artículo
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