Acupoint-injection of BCG polysaccharide nuclear acid for treatment of condyloma acuminatum and its immunoregulatory action on the patient / 中国针灸
Chinese Acupuncture & Moxibustion
;
(12): 407-411, 2007.
Artículo
en Chino
| WPRIM
| ID: wpr-351854
ABSTRACT
<p><b>OBJECTIVE</b>To probe into immunological mechanisms and clinical therapeutic effect of acupoint-injection of BCG polysaccharide nuclear acid (BCG-PSN) for treatment of condyloma acuminatum (CA).</p><p><b>METHODS</b>Two hundred cases were randomly divided into 4 groups. After removed the CA by laser, the treatment group (group A) was treated with acupoint-injection of BCG-PSN, the control group I (group B) with intramuscular injection of BCG-PSN, the control group II (group C) with intramuscular injection of interferon, and the blank control group (group D) with no treatment. The levels of cellular immune function were detected before treatment and after treatment of 6 months, and the cases of relapse were recorded.</p><p><b>RESULTS</b>The cured rate of 94.3% in the group A was significantly higher than 78.0% in the group B, 80.4% in the group C and 78.2% in the group D, with significant differences (P < 0.05); in the group A, CD4+ percent increased, CD8+ percent decreased, CD4+ /CD+ ratio increased, and NK cell activity increased with a low relapse rate, and with significant differences as compared with the control groups (P < 0.05, P < 0.01).</p><p><b>CONCLUSION</b>Acupoint-injection of BCG-PSN has a better therapeutic effect and it can obviously reduce the recurrence rate of CA. The cellular immunoregulatory action is one of the mechanisms of this therapy in preventing relapse of CA.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Polisacáridos Bacterianos
/
Terapéutica
/
Vacuna BCG
/
Ácidos Nucleicos
/
Células Asesinas Naturales
/
Condiloma Acuminado
/
Puntos de Acupuntura
/
Relación CD4-CD8
/
Alergia e Inmunología
/
Inyecciones
Límite:
Adolescente
/
Adulto
/
Femenino
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
Chinese Acupuncture & Moxibustion
Año:
2007
Tipo del documento:
Artículo
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