Biomechanical study on open fracture model with plate fixation compared with closed fracture model with intramedullary nail fixation in rats / 中国骨伤
China Journal of Orthopaedics and Traumatology
;
(12): 676-680, 2013.
Artículo
en Chino
| WPRIM
| ID: wpr-353043
ABSTRACT
<p><b>OBJECTIVE</b>To compare biomechanical effect of the closed fracture model with intramedullary nail fixation and the open fracture model with plate fixation in rats.</p><p><b>METHODS</b>Forty 8-week-old Spragu-Dawley male rats were divided into two groups randomly. Left femoral shaft closed fractures model was created in 20 rats, and treated with intramedullary nail. Other 20 rats received open osteotomy on the left femoral shaft, and were fixed by plate. Rats were sacrificed and draw the materials at 4, 6, 8 and 12 weeks in batch. Across section area and volume of callus were measured, peak load, restoration rate of peak load were tested. The biomechanical efficency of two methods of femoral shaft fracture fixation were compared.</p><p><b>RESULTS</b>The difference of surgical duration was statistically significant between two groups (P < 0.001). At 4, 6, 8 and 12 weeks, the difference of peak load, restoration rate of peak load, volume and area of callus was also statistically significant between two groups (P < 0.05).</p><p><b>CONCLUSION</b>Open fracture model with plate fixation led to delayed healing compared with closed fracture model with intramedullary nail. However, open fracture model with plate fixation model could be a valuable research tool to study the healing consequences of cortical bone, which may provide insight into the pathogenesis and ideal treatment of fractures or nonunions.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Cirugía General
/
Fenómenos Biomecánicos
/
Placas Óseas
/
Ratas Sprague-Dawley
/
Fijación Interna de Fracturas
/
Fijación Intramedular de Fracturas
/
Fracturas Cerradas
/
Fracturas Abiertas
/
Métodos
Límite:
Animales
Idioma:
Chino
Revista:
China Journal of Orthopaedics and Traumatology
Año:
2013
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS