The biotransformation of kaempferitrin by human intestinal flora / 药学学报
Acta Pharmaceutica Sinica
;
(12): 717-721, 2005.
Artículo
en Chino
| WPRIM
| ID: wpr-353422
ABSTRACT
<p><b>AIM</b>To study the biotransformation of kaempferitrin, a major chemical principle of the fruits of Siraitia grosvenori (Swingle) C. Jeffery, with human intestinal flora.</p><p><b>METHODS</b>The kaempferitrin was incubated with human intestinal flora. The biotransformation products were isolated and purified by chromatographic methods and the structures were determined by spectroscopic techniques.</p><p><b>RESULTS</b>Kaempferitrin was converted into kaempferol 3-O-alpha-L-rhamnoside (afzelin, I) , kaempferol 7-O-alpha-L-rhamnoside (II), kaempferol (III) and p-hydroxybenzoic acid (IV) by human intestinal flora. rhamnoside (II), kaempferol (III) and p-hydroxybenzoic acid (IV) by human intestinal flora.</p><p><b>CONCLUSION</b>The structure of kaempferitrin can be biotransformatedly converted by human intestinal flora.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Parabenos
/
Plantas Medicinales
/
Bacterias
/
Farmacocinética
/
Biotransformación
/
Química
/
Momordica
/
Quempferoles
/
Proantocianidinas
/
Frutas
Límite:
Humanos
Idioma:
Chino
Revista:
Acta Pharmaceutica Sinica
Año:
2005
Tipo del documento:
Artículo
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