Studies on lignan glycosides from the roots of Bupleurum scorzonerifolium / 药学学报
Acta Pharmaceutica Sinica
; (12): 428-431, 2005.
Article
en Zh
| WPRIM
| ID: wpr-353442
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>AIM</b>To study the lignan glycosides from the roots of Bupleurum scorzonerifolium. Chromatography methods was used to isolate compounds and chemical and spectral methods were used to identify the structures of isolated compounds.</p><p><b>RESULTS</b>Two lignan glycosides were isolated from the roots of B. scorzonerifolium and their structures were identified as 2, 3-E-2,3-dihydro-2-(3'-methoxy-4'-O-beta-D-glucopyranosyl-phenyl)-3-hydroxymethyl-5-(3"-hydroxypropenyl )-7-methoxy-1-benzo [b] furan (1) and 2, 3-E-2, 3-dihydro-2-( 3'-methoxy-4'-hydroxy-phenyl)-3-hydroxymethyl-5-( 3"-hydroxypropenyl)-7-O-beta-D-glucopyranosyl-1-benzo[b]furan (2), both of them which were the mixture of (+)2S,3R- and (-)2R,3S-type diastereoisomer and in both of them the amount of (+)2S,3R-type was a little more than that of the (-)2R,3S-type.</p><p><b>CONCLUSION</b>Compounds 1 and 2 were isolated from B. scorzonerifolium for the first time. (+)2S, 3R-2, 3-Dihydro-2-(3'-methoxy-4'-hydroxy-phenyl)-3-hydroxymethyl-5-(3"-hydroxypropenyl)-7-O-beta-D-glucopyranosyl-1-benzo[b] furan is a new compound.</p>
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1
Índice:
WPRIM
Asunto principal:
Plantas Medicinales
/
Química
/
Lignanos
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Raíces de Plantas
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Bupleurum
/
Glicósidos
/
Conformación Molecular
Tipo de estudio:
Prognostic_studies
Idioma:
Zh
Revista:
Acta Pharmaceutica Sinica
Año:
2005
Tipo del documento:
Article