Preparation of 5-fluorouracil-peanut agglutinin conjugate and determination of the ratio of drug to conjugate / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 545-547, 2005.
Artículo
en Chino
| WPRIM
| ID: wpr-354254
ABSTRACT
5-fluorouracil was combined with peanut agglutinin by a water-soluble carbodiimide to prepare the tumor target conjugate of 5-fluorouracil-peanut agglutinin and the ratio of drug to conjugate was determined by the modified trinitrobenzenesulfonic acid method (TNBS). The ratio of drug to conjugate was 76.33%. The result showed that 5-fluorouracil could link to the peanut agglutinin by EDC/NHS crosslinking with high drug ratio.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Química
/
Aglutinina de Mani
/
Reactivos de Enlaces Cruzados
/
Fluorouracilo
/
Antineoplásicos
Idioma:
Chino
Revista:
Journal of Biomedical Engineering
Año:
2005
Tipo del documento:
Artículo
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