Research progress on chemokine receptor 5-targeted therapy for HIV-1 / 病毒学报
Chinese Journal of Virology
;
(6): 79-83, 2014.
Artículo
en Chino
| WPRIM
| ID: wpr-356634
ABSTRACT
Along with the spread of human immunodeficiency virus 1 (HIV-1) infection in the world and the emergence of drug-resistant viral strains, it is urgent to seek the novel potent therapies. Chemokine receptor 5 (CCR5) is one of the main coreceptors involved in the entry of HIV-1 into target cells. Nowadays, a number of CCR5 antagonists have been developed and some of them have progressed to clinical trials or been approved. Research progress has also been made in the CCR5-targeted gene therapy. This review summarizes the recent research progress on the CCR5-targeted drug and gene therapy.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Patología
/
Infecciones por VIH
/
VIH-1
/
Receptores CCR5
/
Quimioterapia
/
Terapia Molecular Dirigida
/
Antagonistas de los Receptores CCR5
/
Genética
/
Metabolismo
/
Métodos
Límite:
Humanos
Idioma:
Chino
Revista:
Chinese Journal of Virology
Año:
2014
Tipo del documento:
Artículo
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