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A study of aspermia-related genes by genchips and analysis of the RAP1A gene / 中华男科学杂志
National Journal of Andrology ; (12): 654-657, 2003.
Artículo en Chino | WPRIM | ID: wpr-357117
ABSTRACT
<p><b>OBJECTIVE</b>To study the differential gene expression profiles between the normal and aspermia human testes by genechips.</p><p><b>METHODS</b>Probes were prepared from mRNA extracted from both normal and aspermia testes and employed on Biostar H-40s genechips to detect the differential gene expression profiles. A distinctly up-regulated gene RAP1A was analyzed by bibliogrphic retrieval.</p><p><b>RESULTS</b>Six hundred and twenty-three differential expressed genes were found, among which the distinctly up-regulated gene RAP1A was closely related to human sperm regulation.</p><p><b>CONCLUSIONS</b>Screening the differential gene expression profiles between the normal and aspermia human testes by genechips can be used in the study of aspermia-related genes.</p>
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Oligospermia / Análisis de Secuencia por Matrices de Oligonucleótidos / Proteínas de Unión al GTP rap1 / Perfilación de la Expresión Génica / Genética / Métodos Límite: Adulto / Humanos / Masculino Idioma: Chino Revista: National Journal of Andrology Año: 2003 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Oligospermia / Análisis de Secuencia por Matrices de Oligonucleótidos / Proteínas de Unión al GTP rap1 / Perfilación de la Expresión Génica / Genética / Métodos Límite: Adulto / Humanos / Masculino Idioma: Chino Revista: National Journal of Andrology Año: 2003 Tipo del documento: Artículo