Research advances on the molecular mechanism of autophagy regulated by Porphyromonas gingivalis / 华西口腔医学杂志
West China Journal of Stomatology
; (6): 654-658, 2017.
Article
en Zh
| WPRIM
| ID: wpr-357431
Biblioteca responsable:
WPRO
ABSTRACT
Autophagy is an intracellular conservative degradation pathway. This event has been considered as a key step in host defense against bacterial infection. However, Porphyromonas gingivalis, as one of the evidence-sufficient periodontal pathogens, can utilize self-induced autophagy to achieve persistent intracellular survival and proliferation, which enable this organism to escape from host immune surveillance. This review focuses on molecular mechanism of P. gingivalis internalization and autophagy to illuminate its pathogenesis and to further explore the relationship between P. gingivalis and systemic diseases.
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WPRIM
Idioma:
Zh
Revista:
West China Journal of Stomatology
Año:
2017
Tipo del documento:
Article