Optimization study on extraction technology of the seed of Ziziphus jujuba var. spinosa by orthogonal design with multi-targets / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To optimize extraction technology of the seed of Ziziphus jujuba var. spinosa with the targets of the total saponin, total jujuboside A and B and total flavonoids.</p><p><b>METHOD</b>In the method of one-way and orthogonal tests, ethanol concentration, amount of ethanol, extraction time and extraction times were the factors in orthogonal test, and each factor with three levels.</p><p><b>RESULT</b>Ethanol concentration and extraction times had significant effect on all the targets, other factors should be selected in accordance with production practice.</p><p><b>CONCLUSION</b>The best extraction technology is to extract for three times with 8 fold ethanol solution (60%), and 1.5 h each time.</p>