Changes of blood viscosity and erythrocyte rheology in acute hypoxic hypoxia mices / 中国应用生理学杂志
Chinese Journal of Applied Physiology
;
(6): 454-457, 2012.
Artículo
en Chino
| WPRIM
| ID: wpr-358716
ABSTRACT
<p><b>OBJECTIVE</b>To observe the changes of blood viscosity and erythrocyte rheology in mice after acute hypoxic hypoxia (AHH).</p><p><b>METHODS</b>Thirty-two Kui-ming mice were randomly divided into control group, AHH group (duplicating AHH model, and divided into 5 min, 8 min, 11 min subgroups), the blood sample was taken out from heart after neck dislocation at corresponding times, for detecting the blood viscosity and erythrocyte rheology indices.</p><p><b>RESULTS</b>Compared with control group, the whole blood viscosity at different shears, whole blood reduced viscosity, whole blood relative viscosity were lower and the erythrocytes aggregation index was higher in AHH 5 min group; the electrophoresis time was longer and the electrophoresis length, migration of erythrocyte were lower in AHH 8 min and AHH 11 min groups. The whole blood reduced viscosity, whole blood relative viscosity, erythrocytes aggregation index in AHH 8 min group were higher, and the erythrocyte deformability index was lower significantly than that of AHH 5 min group, respectively.</p><p><b>CONCLUSION</b>These data suggested that the AHH could induce the blood viscosity and electrophoresis ability.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fisiología
/
Sangre
/
Viscosidad Sanguínea
/
Agregación Eritrocitaria
/
Deformación Eritrocítica
/
Índices de Eritrocitos
/
Eritrocitos
/
Hipoxia
/
Ratones Endogámicos
Límite:
Animales
Idioma:
Chino
Revista:
Chinese Journal of Applied Physiology
Año:
2012
Tipo del documento:
Artículo
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