Bone Marrow Microenvironment and Myelodysplastic Syndromes--Review / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 290-294, 2016.
Artículo
en Chino
| WPRIM
| ID: wpr-360099
ABSTRACT
Myelodysplastic syndromes (MDS) are a group of bone marrow failure diseases. The bone marrow microenvironment consists of bone marrow stromal cells (BMSC), growth factors and cytokines. The BMSC supporting haemopoiesis include mesenchymal stem cells (MSC), osteoblasts, endothelial cells and macrophages, but the adipocytes play a role in the suppression of hematopoiesis. Recently more and more researches indicate that the abnormality of bone marrow microenvironment involves in the pathogenesis and progression of MDS. In this review the abnormality of MDS bone marrow microenvironment is summarized briefly.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Médula Ósea
/
Síndromes Mielodisplásicos
/
Citocinas
/
Progresión de la Enfermedad
/
Péptidos y Proteínas de Señalización Intercelular
/
Células Madre Mesenquimatosas
/
Microambiente Celular
/
Hematopoyesis
Límite:
Humanos
Idioma:
Chino
Revista:
Journal of Experimental Hematology
Año:
2016
Tipo del documento:
Artículo
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