A Case of Re-operation for Paravalvular Leakage after Mitral Valve Replacement Complicated by Heparin-Induced Thrombocytopenia / 日本心臓血管外科学会雑誌
Japanese Journal of Cardiovascular Surgery
; : 112-114, 2011.
Article
en Ja
| WPRIM
| ID: wpr-362075
Biblioteca responsable:
WPRO
ABSTRACT
Anticoagulation management in cardiac surgery can be difficult in patients with heparin-induced thrombocytopenia (HIT). We report a patient who underwent reoperation of cardiopulmonary bypass (CPB) using argatroban in combination with nafamostat mesilate. A bolus of 0.25 mg/kg argatroban was administered, followed by continuous infusion of 5-10 μg/kg/min argatroban and 100 mg/h nafamostat mesilate. No complications such as thrombosis were observed during either CPB or the perioperative period. Although we used argatroban and nafamostat mesilate, which has a shorter half-life than argatroban, the anticoagulant effect was prolonged, and the patient had an uneventful postoperative course despite requiring substantial blood transfusion.
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Índice:
WPRIM
Idioma:
Ja
Revista:
Japanese Journal of Cardiovascular Surgery
Año:
2011
Tipo del documento:
Article