Safety Evaluation of Fucoidan from Kjellmaniella Crassifolia in Genotoxicity Tests / 日本補完代替医療学会誌
Japanese Journal of Complementary and Alternative Medicine
; : 61-65, 2011.
Article
en Ja
| WPRIM
| ID: wpr-376524
Biblioteca responsable:
WPRO
ABSTRACT
We evaluated the safety of fucoidan from Gagome Kombu (GKF) in genotoxicity tests. In bacterial reverse mutation test, GKF had no reverse mutation inducing activity on five bacterial strains with or without S9 metabolic activation. In chromosome aberration test, GKF had neither structural nor numerical chromosome aberration inducibility with or without S9 metabolic activation. In micronucleus test, neither formation of micronuclei nor decrease of mironucleated reticulocytes was observed in the bone marrow of the mice treated by GKF. These results indicate that GKF has no genotoxic activities under the condition of this study.<br>
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Índice:
WPRIM
Idioma:
Ja
Revista:
Japanese Journal of Complementary and Alternative Medicine
Año:
2011
Tipo del documento:
Article