Endoscopic ultrasonography and endoscopic retrograde cholangiopancreatography in chronic pancreatitis / 中华消化内镜杂志

ABSTRACT

Objective To evaluate the sensitivity and specificity of endoscopic uhrasonography (EUS) and endoscopic retrograde cholangiopancreatography(ERCP)in diagnosis of chronic pancrea (CP).Methods Data of histologically confirmed CP cases,from May 1994 to May 2004 in 22 Chinese hospitals,were retrospectively analyzed.The receiver operating characteristic(ROC)was used to compare the sensitivity and specificity of EUS and ERCP.Results The data of 1994 CP cases were retrieved,including 1298 males and 696 females.aging from 5 to 85(48.9±15.0).The diagnosis of CP was confirmed histologitally in 239 patients(11.98%),and pancreatic exocrine function test(BT-PABA)were employed in 261 patients(13.09%),X-ray in 419(20.86%),B ultrasonography in 1424(71.41%),CT in 889 (44.58%),magnetic resonance imaging(MRI)and magnetic resonance cholangiopancreatography(MRCP) in 245(12.29%),ERCP in 628(31.49%),and EUS in 258(12.94%).The sensitivity and specificity of each method were as follows88% and 93% for EUS.87% and 93% for ERCP,66% and 85% for MRI and MRCP,61% and 85% for CT,69% and 82% for B ultrasonography,32%and 80%for X ray,83% and 80% for BT-PABA.Conclusion Of all the diagnostic methods,EUS and ERCP are the most sensitive and specific to diagnose of CP,while EUS is of the highest.