Expression and clinical significance of Her-2/neu and Topo Ⅱ α protein in gastric cancer / 肿瘤研究与临床
Cancer Research and Clinic
;
(6): 65-67, 2011.
Artículo
en Chino
| WPRIM
| ID: wpr-382900
ABSTRACT
Protocarcinogenic gene Her-2/neu was closely related to the development of gastric cancer. Herceptin is an antibody according to Her-2/neu and is used for treating breast cancer. Topo Ⅱ α is the important Nuclear enzymes needed by DNA duplicate, and is closely related to the proliferation of malignant tumors, so it is the important target enzymes of cancer chemotherapy. Her-2/neu and Topo Ⅱ α are located in the same chromosomes, there are correlation between the two genes' proliferation or loss. We reviewed the expression of Her-2/neu and Topo Ⅱ α in the stomach and the new progress of the correlation between the two genes home and abroad in this paper, which provides new methods for the prevention and treatment of gastric cancer.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Cancer Research and Clinic
Año:
2011
Tipo del documento:
Artículo
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