A Case of Doxifluridine-Induced Ro/SSA-Positive Cutaneous Lupus Erythematosus / 대한피부과학회지

ABSTRACT

Anti-Ro/SSA antibody positive drug-induced lupus erythematosus is characterized by erythematous papules at the photodistributed area after drug intake, positive anti-Ro/SSA antibody tests and histopathologic features of lupus erythematosus. A 68-year-old man was referred to our clinic with multiple erythematous violacious plaques on the face of 2 months' duration. After surgical removal of stomach cancer, he had been taking doxifluridine for 10 months. A histopathologic study revealed findings consistent with lupus erythematosus and the anti-Ro/SSA antibody was positive on the serologic test. Based on these findings, we diagnosed this case as anti-Ro/SSA antibody positive drug-induced lupus erythematosus, and report it with review of the literature.