Current trends in molecular classification of cancers / 中华检验医学杂志

ABSTRACT

Tumor morphology from the microscopic appearance has being served as the basis of tumor classification,but has serious 1imitations.Molecular aberrations,including DNA,RNA and protein,ale playing an ever increasing role in guiding classification,prognosis,and therapeutic strategies in cancer patients.A specific molecular profile correlating with important clinical parameters should allow physicians to base management decisions on the molecular characteristics of an individual patient's tumor.The application of high-throughput technologies to tumor,3 should make it possible to generate comprehensive molecular profiles.The integration of clinical,morphological and molecular data could result in a more precise classification of cancers,and lead to better understanding,individualized predicting and treatment,which would give the maximum benefit to the patients.