Clinical efficacy of pioglitazone combined with metformin in type 2 diabetes patients / 中国基层医药

ABSTRACT

Objective To observe the effects of pioglitazone combined with metformin in type 2 diabetes.Methods 152 type 2 diabetes patients were randomly divided into control group and treatment group.The control group was treated with metformin 0.5g,3 time every day.The treatment group received pioglitazone 30mg,one time every day,except took metformin 0.5 g,3 time every day.Two groups all completed a therapeutic period of 3 months.Results The effect of the treatment group compared with the control group has significantly statistical difference(P＜0.05).Fasting blood glucose and postprandial blood glucosecompared back and forth,the treatment group and control group all have significantly statistical difference(all P＜0.05);the result of the treatment group compared with that of the control group has significant difference also(all P＜0.05).Conclusion The therapeutic effect of pioglitazone combined with metformin on type 2 diabetes patients was much better than metformin only.