Usefulness of Brachial-Ankle Pulse Wave Velocity and Ankle-Brachial Index as Predictors of Early Age-Related Maculopathy
Journal of the Korean Ophthalmological Society
;
: 696-701, 2011.
Artículo
en Coreano
| WPRIM
| ID: wpr-38700
ABSTRACT
PURPOSE:
Age-related maculopathy (ARM) is a major cause of blindness. For this reason, an early predictor of ARM is necessary for early detection and preventive therapy. The present study investigated arterial stiffness and stenosis using ankle brachial index (ABI) and pulse wave velocity (PWV) and analyzed whether arterial stiffness was affected by the extent of ARM.METHODS:
A total of 257 randomized patients were enrolled in the present study. All participants underwent baPWV, ABI, blood pressure, total cholesterol, and triglyceride evaluation and were questioned regarding their history of smoking. The extent of ARM was expressed using Wisconsin ARM grading.RESULTS:
Of the 257 patients, 29 were diagnosed with early ARM using Wisconsin ARM grading. The average age of the ARM group was 53 +/- 6.56 years and was significantly greater than the average 45.93 +/- 8.61 years in the non-ARM group. Other than ankle-brachial index, the clinical variables showed no significant differences after a refining process for age-related variables. Ankle-brachial index was significantly lower in the ARM group than it was in the non-ARM group (1.08 +/- 0.052, 1.12 +/- 0.051, respectively).CONCLUSIONS:
The ARM group showed significantly increased arterial stenosis. The present study provides a basis for the use of PWV in the early detection of ARM; however, longitudinal studies employing a larger population are required to determine the diagnostic and prognostic implications of PWV in ARM.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Brazo
/
Humo
/
Presión Sanguínea
/
Fumar
/
Wisconsin
/
Ceguera
/
Colesterol
/
Constricción Patológica
/
Índice Tobillo Braquial
/
Rigidez Vascular
Tipo de estudio:
Ensayo Clínico Controlado
/
Estudio observacional
/
Estudio pronóstico
/
Estudio de tamizaje
Límite:
Humanos
País/Región como asunto:
America del Norte
Idioma:
Coreano
Revista:
Journal of the Korean Ophthalmological Society
Año:
2011
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS