Small molecule inhibitors of Bcl-2 proteins:research progress / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 579-581, 2010.
Artículo
en Chino
| WPRIM
| ID: wpr-387501
ABSTRACT
Small molecule inhibitors of Bcl-2 are a novel class of anticancer drugs that target anti-apoptotic proteins. In recent years,small molecule inhibitors such as ABT-737 ,ABT-263, gossypol, apogossypol,TW-37,obatoclax, HAl4-1 have attracted much reseach attention. Preclinical trials have shown that the inhibitors have cancer killing effect on some tumors when used alone and exhibit striking synergistic effect when combined with radiotherapy and/or chemotherapy.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of International Oncology
Año:
2010
Tipo del documento:
Artículo
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